4.5 Article

New benzimidazoles as thrombopoietin receptor agonists

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 16, Issue 5, Pages 1212-1216

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.11.096

Keywords

thrombopoietin; benzimidazole; receptor agonist; structure-activity relationships

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A novel benzimidazole series of small-molecule thrombopoietin receptor agonists has been discovered. Herein, we discuss the preliminary exploration of structure-activity relationships within this chemotype. (C) 2005 Elsevier Ltd. All rights reserved.

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