Related references
Note: Only part of the references are listed.IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation
Keng-Mean Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation
Naeha Subramanian et al.
CELL (2013)
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
Kairui Mao et al.
CELL RESEARCH (2013)
Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome
Ali A. Abdul-Sater et al.
EMBO REPORTS (2013)
Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
Shankar S. Iyer et al.
IMMUNITY (2013)
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
Raul Munoz-Planillo et al.
IMMUNITY (2013)
Deubiquitinases Regulate the Activity of Caspase-1 and Interleukin-1β Secretion via Assembly of the Inflammasome
Gloria Lopez-Castejon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
An Interaction between Bcl-xL and the Voltage-dependent Anion Channel (VDAC) Promotes Mitochondrial Ca2+ Uptake
Huiya Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation
Kathy Triantafilou et al.
JOURNAL OF CELL SCIENCE (2013)
Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
Teresa Fernandes-Alnemri et al.
JOURNAL OF IMMUNOLOGY (2013)
The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
Sangjun Park et al.
JOURNAL OF IMMUNOLOGY (2013)
Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein
Manira Rayamajhi et al.
JOURNAL OF IMMUNOLOGY (2013)
Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity
Benedicte F. Py et al.
MOLECULAR CELL (2013)
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1 beta
Bibhuti B. Mishra et al.
NATURE IMMUNOLOGY (2013)
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
Takuma Misawa et al.
NATURE IMMUNOLOGY (2013)
Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection
Takeshi Ichinohe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
TRPM2 links oxidative stress to NLRP3 inflammasome activation
Zhenyu Zhong et al.
NATURE COMMUNICATIONS (2013)
An update on PYRIN domain-containing pattern recognition receptors: from immunity to pathology
Rojo A. Ratsimandresy et al.
FRONTIERS IN IMMUNOLOGY (2013)
Activation and regulation of the inflammasomes
Eicke Latz et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Inflammasomes and Their Roles in Health and Disease
Mohamed Lamkanfi et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 28 (2012)
Cell Volume Regulation Modulates NLRP3 Inflammasome Activation
Vincent Compan et al.
IMMUNITY (2012)
An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
Sonal Khare et al.
IMMUNITY (2012)
Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1
Olaf Gross et al.
IMMUNITY (2012)
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada et al.
IMMUNITY (2012)
Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
Kate Schroder et al.
IMMUNOBIOLOGY (2012)
Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
Christine Juliana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223
Franz Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2012)
Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1β Production
Moritz Haneklaus et al.
JOURNAL OF IMMUNOLOGY (2012)
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
Geun-Shik Lee et al.
NATURE (2012)
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Chong-Shan Shi et al.
NATURE IMMUNOLOGY (2012)
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
Tomohiko Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
Manuela Rossol et al.
NATURE COMMUNICATIONS (2012)
Is mPTP the gatekeeper for necrosis, apoptosis, or both?
Kathleen W. Kinnally et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
Eran Elinav et al.
CELL (2011)
Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
Andrea Rasola et al.
CELL CALCIUM (2011)
BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane
Z. T. Schug et al.
CELL DEATH AND DIFFERENTIATION (2011)
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
Nagaraj Kerur et al.
CELL HOST & MICROBE (2011)
Cellular Inhibitors of Apoptosis Proteins cIAP1 and cIAP2 Are Required for Efficient Caspase-1 Activation by the Inflammasome
Katherine Labbe et al.
IMMUNITY (2011)
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
Greta Guarda et al.
IMMUNITY (2011)
Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice
Jae Jin Chae et al.
IMMUNITY (2011)
NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate of Toxoplasma gondii-Infected Monocytic Cells
William H. Witola et al.
INFECTION AND IMMUNITY (2011)
Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
Franz Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
Yue Zhao et al.
NATURE (2011)
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
Eric M. Kofoed et al.
NATURE (2011)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
Critical functions of priming and lysosomal damage for NLRP3 activation
Veit Hornung et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Signaling by ROS drives inflammasome activation
Fabio Martinon
EUROPEAN JOURNAL OF IMMUNOLOGY (2010)
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
Hendrik Poeck et al.
NATURE IMMUNOLOGY (2010)
Intracellular DNA recognition
Veit Hornung et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Immunological and Inflammatory Functions of the Interleukin-1 Family
Charles A. Dinarello
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Mohamed Lamkanfi et al.
JOURNAL OF CELL BIOLOGY (2009)
Cutting Edge: TNF-α Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation
Luigi Franchi et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes
Greta Guarda et al.
NATURE (2009)
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Teresa Fernandes-Alnemri et al.
NATURE (2009)
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
Veit Hornung et al.
NATURE (2009)
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
Tilmann Buerckstuemmer et al.
NATURE IMMUNOLOGY (2009)
HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA
Tara L. Roberts et al.
SCIENCE (2009)
Role of phospholipid scramblase 3 in the regulation of tumor necrosis factor-α-induced apoptosis
Jihua Liu et al.
BIOCHEMISTRY (2008)
The NLR gene family: A standard nomenclature
Jenny P. -Y. Ting et al.
IMMUNITY (2008)
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
Francois Gonzalvez et al.
JOURNAL OF CELL BIOLOGY (2008)
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
Jonathan B. Johnnidis et al.
NATURE (2008)
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
NATURE (2008)
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
V. Petrilli et al.
CELL DEATH AND DIFFERENTIATION (2007)
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T. Fernandes-Alnemri et al.
CELL DEATH AND DIFFERENTIATION (2007)
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
Annick Mayor et al.
NATURE IMMUNOLOGY (2007)
Bcl-2 and Bcl-XL regulate proinf lammatory caspase-1 activation by interaction with NALP1
Jean-Marie Bruey et al.
CELL (2007)
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
Susan L. Fink et al.
CELLULAR MICROBIOLOGY (2006)
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
ED Boyden et al.
NATURE GENETICS (2006)
Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit:: implications for apoptosis and neurodegenerative disease
R Clayton et al.
JOURNAL OF NEUROCHEMISTRY (2005)
NALP3 forms an IL-lβ-Processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
L Agostini et al.
IMMUNITY (2004)
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
S Mariathasan et al.
NATURE (2004)
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID) -: A new member of the expanding family of pyrin-associated autoinflammatory diseases
I Aksentijevich et al.
ARTHRITIS AND RHEUMATISM (2002)
The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
F Martinon et al.
MOLECULAR CELL (2002)
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
J Feldmann et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)
Cytochrome c release from mitochondria proceeds by a two-step process
M Ott et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
HM Hoffman et al.
NATURE GENETICS (2001)