Journal
STEROIDS IN NEUROENDOCRINE IMMUNOLOGY AND THERAPY OF RHEUMATIC DISEASES II
Volume 1318, Issue -, Pages 65-70Publisher
BLACKWELL SCIENCE PUBL
DOI: 10.1111/nyas.12436
Keywords
juvenile idiopathic arthritis; corticosteroids; intraarticular injections; systemic juvenile idiopathic arthritis; chronic iridocyclitis; macrophage activation syndrome
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Although the use of corticosteroids in juvenile idiopathic arthritis (JIA) is now much more limited owing to the availability of methotrexate and biological agents, there are clinical scenarios where it is still indicated. For example, corticosteroids may be indicated for intraarticular injections to prevent joint deformities, as a bridge drug to relieve symptoms in polyarticular disease while waiting for methotrexate and biologics to exert their full therapeutic effects, and in the treatment of chronic iridocyclitis, macrophage activation syndrome, and systemic JIA, although the advent of interleukin (IL)-1 and IL-6 blockers has greatly reduced the latter indication.
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