Related references
Note: Only part of the references are listed.Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance
N. B. Jorgensen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
Chutima Talchai et al.
CELL (2012)
Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo
Olov Andersson et al.
CELL METABOLISM (2012)
Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome
Christine M. Oslowski et al.
CELL METABOLISM (2012)
IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress
Alana G. Lerner et al.
CELL METABOLISM (2012)
Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice
Alireza Rezania et al.
DIABETES (2012)
β-Cell Function Preservation After 3.5 Years of Intensive Diabetes Therapy
Lindsay B. Harrison et al.
DIABETES CARE (2012)
Prognostic Accuracy of Immunologic and Metabolic Markers for Type 1 Diabetes in a High-Risk Population Receiver operating characteristic analysis
Ping Xu et al.
DIABETES CARE (2012)
A tale of two glucose transporters: how GLUT2 re-emerged as a contender for glucose transport into the human beta cell
M. van de Bunt et al.
DIABETOLOGIA (2012)
Imaging of β-Cell Mass and Insulitis in Insulin-Dependent (Type 1) Diabetes Mellitus
Valentina Di Gialleonardo et al.
ENDOCRINE REVIEWS (2012)
Minireview: The Role of the Autonomic Nervous System in Mediating the Glucagon Response to Hypoglycemia
Gerald J. Taborsky et al.
ENDOCRINOLOGY (2012)
Glutathionylation State of Uncoupling Protein-2 and the Control of Glucose-stimulated Insulin Secretion
Ryan J. Mailloux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Formation of a Human β-Cell Population within Pancreatic Islets Is Set Early in Life
Brigid E. Gregg et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells
Thomas C. Schulz et al.
PLOS ONE (2012)
Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication
Justin P. Annes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Glucagon secretion and signaling in the development of diabetes
Herbert Y. Gaisano et al.
FRONTIERS IN PHYSIOLOGY (2012)
beta-Cell Dysfunctional ERAD/Ubiquitin/Proteasome System in Type 2 Diabetes Mediated by Islet Amyloid Polypeptide-Induced UCH-L1 Deficiency
Safia Costes et al.
DIABETES (2011)
A Low-Oxygenated Subpopulation of Pancreatic Islets Constitutes a Functional Reserve of Endocrine Cells
Richard Olsson et al.
DIABETES (2011)
The dual control of insulin secretion by glucose involves triggering and amplifying pathways in β-cells
Jean-Claude Henquin
DIABETES RESEARCH AND CLINICAL PRACTICE (2011)
Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice
H. E. Levitt et al.
DIABETOLOGIA (2011)
Pancreatic alpha cell mass in European subjects with type 2 diabetes
J. C. Henquin et al.
DIABETOLOGIA (2011)
Islets Transplanted in Immunoisolation Devices: A Review of the Progress and the Challenges that Remain
Esther S. O'Sullivan et al.
ENDOCRINE REVIEWS (2011)
Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients
Jason L. Gaglia et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion
Philippe Ravassard et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Beta-Cell Failure, Stress, and Type 2 Diabetes
Randal J. Kaufman
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog
Thomas Reiner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Evidence for Proteotoxicity in β Cells in Type 2 Diabetes Toxic Islet Amyloid Polypeptide Oligomers Form Intracellularly in the Secretory Pathway
Tatyana Gurlo et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Insulin Reciprocally Regulates Glucagon Secretion in Humans
Benjamin A. Cooperberg et al.
DIABETES (2010)
Parathyroid Hormone-Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression
Nagesha Guthalu Kondegowda et al.
DIABETES (2010)
Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6
Nathalie M. Fiaschi-Taesch et al.
DIABETES (2010)
β-Cell Replication Is Increased in Donor Organs From Young Patients After Prolonged Life Support
Peter In't Veld et al.
DIABETES (2010)
beta-Cell Growth and Regeneration: Replication Is Only Part of the Story
Susan Bonner-Weir et al.
DIABETES (2010)
Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study
Hillary A. Keenan et al.
DIABETES (2010)
The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
M. Cnop et al.
DIABETOLOGIA (2010)
Contribution of postnatally formed small beta cell aggregates to functional beta cell mass in adult rat pancreas
M. Chintinne et al.
DIABETOLOGIA (2010)
Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass
G. Fontes et al.
DIABETOLOGIA (2010)
Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats
Wan-Chun Li et al.
JOURNAL OF CELL SCIENCE (2010)
Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined by in Vivo Thymidine Analog Incorporation and Radiocarbon Dating
S. Perl et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Current Status of Islet Cell Replacement and Regeneration Therapy
Philippe A. Halban et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
FoxM1 Is Up-Regulated by Obesity and Stimulates β-Cell Proliferation
Dawn Belt Davis et al.
MOLECULAR ENDOCRINOLOGY (2010)
Protective Unfolded Protein Response in Human Pancreatic Beta Cells Transplanted into Mice
Jeffrey Kennedy et al.
PLOS ONE (2010)
Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes
Lorella Marselli et al.
PLOS ONE (2010)
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
Meritxell Rovira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic β-like cells
Zaida Alipio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Current Advances and Travails in Islet Transplantation
David M. Harlan et al.
DIABETES (2009)
Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass
V. Delghingaro-Augusto et al.
DIABETOLOGIA (2009)
C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
Carlos E. B. Couri et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
11C-Dihydrotetrabenazine PET of the Pancreas in Subjects with Long-Standing Type 1 Diabetes and in Healthy Controls
Robin Goland et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study
Adam G. Tabak et al.
LANCET (2009)
p38 MAPK Is a Major Regulator of MafA Protein Stability under Oxidative Stress
Takuma Kondo et al.
MOLECULAR ENDOCRINOLOGY (2009)
Glucolipotoxicity of the pancreatic β-cell: myth or reality?
Vincent Poitout
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes
Miriam Cnop
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Pancreatic β-cell mass in European subjects with type 2 diabetes
J. Rahier et al.
DIABETES OBESITY & METABOLISM (2008)
Stimulation of human and rat islet β-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1
Jonathan C. Schisler et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Reprogramming pancreatic exocrine cells to β-cells
[Anonymous]
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
Akari Inada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
Qiao Zhou et al.
NATURE (2008)
Partial pancreatectomy in adult humans does not provoke beta-cell regeneration
Bjoern A. Menge et al.
DIABETES (2008)
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress-mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
Chang-jiang Huang et al.
DIABETES (2007)
Glucose infusion in mice -: A new model to induce β-cell replication
Laura C. Alonso et al.
DIABETES (2007)
Insulin receptors in β-cells are critical for islet compensatory growth response to insulin resistance
Terumasa Okada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Biology of incretins: GLP-1 and GIP
Laurie L. Baggio et al.
GASTROENTEROLOGY (2007)
Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance
Yasuo Terauchi et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Recovery from diabetes in mice by beta cell regeneration
Tomer Nir et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Regulation of pancreatic β-cell regeneration in the normoglycemic 60% partial-pancreatectomy mouse
Mina Peshavaria et al.
DIABETES (2006)
Xenotransplantation of purified pre-natal porcine beta cells in mice normalizes diabetes when a short anti-CD4-CD8 antibody treatment is combined with transient insulin injections
Peter In't Veld et al.
XENOTRANSPLANTATION (2006)
Expansion and redifferentiation of adult human pancreatic islet cells
L Ouziel-Yahalom et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates
BJ Hering et al.
NATURE MEDICINE (2006)
Outcomes of pancreas transplants for patients with type 2 diabetes mellitus
DS Nath et al.
CLINICAL TRANSPLANTATION (2005)
Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia
ME Patti et al.
DIABETOLOGIA (2005)
Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro
JH Moffitt et al.
DIABETOLOGIA (2005)
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
C Kjorholt et al.
DIABETES (2005)
Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice
P Rao et al.
DIABETES (2005)
A single course of anti-CD3 monoclonal antibody hOKT3γ1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
KC Herold et al.
DIABETES (2005)
Islet amyloid: A critical entity in the pathogenesis of type 2 diabetes
RL Hull et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Five stages of evolving β-cell dysfunction during progression to diabetes
GC Weir et al.
DIABETES (2004)
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
Y Dor et al.
NATURE (2004)
Selective β-cell loss and β-cell expansion in patients with type 2 diabetes mellitus in Korea
KH Yoon et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Restoration of euglycemia and normal acute insulin response to glucose in obese subjects with type 2 diabetes following bariatric surgery
EV Polyzogopoulou et al.
DIABETES (2003)
Critical reduction in β-cell mass results in two distinct outcomes over time -: Adaptation with impaired glucose tolerance or decompensated diabetes
DR Laybutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
AE Butler et al.
DIABETES (2003)
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
K Maedler et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Glucose-regulated proinsulin gene expression is required for adequate insulin production during chronic glucose exposure
G Leibowitz et al.
ENDOCRINOLOGY (2002)
Genetic regulation of metabolic pathways in β-cells disrupted by hyperglycemia
DR Laybutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
WC Knowler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to β-cell survival during chronic hyperglycemia
DR Laybutt et al.
DIABETES (2002)
Direct measurement of pulsatile insulin secretion from the portal vein in human subjects
SH Song et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2000)
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
S Ferber et al.
NATURE MEDICINE (2000)