4.7 Article Proceedings Paper

The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems

Related references

Note: Only part of the references are listed.
Review Geriatrics & Gerontology

The role of estrogen deficiency in skin ageing and wound healing

Elaine Emmerson et al.

BIOGERONTOLOGY (2012)

Article Critical Care Medicine

Telomere Length Is a Determinant of Emphysema Susceptibility

Jonathan K. Alder et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Review Hematology

Telomere biology in hematopoiesis and stem cell transplantation

Shahinaz M. Gadalla et al.

BLOOD REVIEWS (2011)

Review Immunology

Immunoaging induced by hematopoietic stem cell aging

Jianwei Wang et al.

CURRENT OPINION IN IMMUNOLOGY (2011)

Article Cell Biology

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

Franklin Zhong et al.

GENES & DEVELOPMENT (2011)

Article Gastroenterology & Hepatology

Constitutional Telomerase Mutations Are Genetic Risk Factors for Cirrhosis

Rodrigo T. Calado et al.

HEPATOLOGY (2011)

Article Gastroenterology & Hepatology

Telomerase Gene Mutations Are Associated with Cirrhosis Formation

Daniel Hartmann et al.

HEPATOLOGY (2011)

Article Biochemistry & Molecular Biology

Phenotypes in mTERT+/- and mTERT-/- Mice Are Due to Short Telomeres, Not Telomere-Independent Functions of Telomerase Reverse Transcriptase

Margaret A. Strong et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

Mariela Jaskelioff et al.

NATURE (2011)

Article Multidisciplinary Sciences

Telomere dysfunction induces metabolic and mitochondrial compromise

Erguen Sahin et al.

NATURE (2011)

Article Multidisciplinary Sciences

Short Telomeres Compromise β-Cell Signaling and Survival

Nini Guo et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Regeneration of the Exocrine Pancreas Is Delayed in Telomere-Dysfunctional Mice

Guido von Figura et al.

PLOS ONE (2011)

Article Biochemistry & Molecular Biology

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

Alessandra Sacco et al.

Article Biochemistry & Molecular Biology

CHK2-independent induction of telomere dysfunction checkpoints in stem and progenitor cells

Kodandaramireddy Nalapareddy et al.

EMBO REPORTS (2010)

Article Hematology

Recent progress in dyskeratosis congenita

Nobuhiro Nishio et al.

INTERNATIONAL JOURNAL OF HEMATOLOGY (2010)

Article Biochemistry & Molecular Biology

Feedback between p21 and reactive oxygen production is necessary for cell senescence

Joao F. Passos et al.

MOLECULAR SYSTEMS BIOLOGY (2010)

Article Multidisciplinary Sciences

Telomere length is inherited with resetting of the telomere set-point

Y. Jeffrey Chiang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Genetics & Heredity

Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging

Mary Armanios et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2009)

Article Biochemistry & Molecular Biology

Dyskeratosis congenita, stem cells and telomeres

Michael Kirwan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)

Article Cell Biology

TCAB1 Driving telomerase to Cajal bodies

Andrew S. Venteicher et al.

CELL CYCLE (2009)

Article Multidisciplinary Sciences

Telomerase modulates Wnt signalling by association with target gene chromatin

Jae-Il Park et al.

NATURE (2009)

Article Genetics & Heredity

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

Yvonne Begus-Nahrmann et al.

NATURE GENETICS (2009)

Article Multidisciplinary Sciences

A Spectrum of Severe Familial Liver Disorders Associate with Telomerase Mutations

Rodrigo T. Calado et al.

PLOS ONE (2009)

Article Multidisciplinary Sciences

A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis

Andrew S. Venteicher et al.

SCIENCE (2009)

Article Genetics & Heredity

TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita

Sharon A. Savage et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2008)

Article Biochemistry & Molecular Biology

Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response

Isabelle Morin et al.

EMBO JOURNAL (2008)

Article Biochemistry & Molecular Biology

TERT promotes cellular and organismal survival independently of telomerase activity

J. Lee et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice

Bai-Wei Gu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo

Sripriya Rajaraman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

Derrick J. Rossi et al.

NATURE (2007)

Article Geriatrics & Gerontology

Hematopoietic stem cell aging: Mechanism and consequence

Derrick J. Rossi et al.

EXPERIMENTAL GERONTOLOGY (2007)

Article Oncology

Short telomeres limit tumor progression in vivo by inducing senescence

David M. Feldser et al.

CANCER CELL (2007)

Article Biochemistry & Molecular Biology

Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence

Wilfredo Cosme-Blanco et al.

EMBO REPORTS (2007)

Article Multidisciplinary Sciences

Protein composition of catalytically active human telomerase from immortal cells

Scott B. Cohen et al.

SCIENCE (2007)

Article Medicine, General & Internal

Telomerase mutations in families with idiopathic pulmonary fibrosis

Mary Y. Armanios et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Multidisciplinary Sciences

Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse

Christine M. Khoo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Stem cells, ageing and the quest for immortality

Thomas A. Rando

NATURE (2006)

Review Immunology

The hematopoietic stem cell in its place

GB Adams et al.

NATURE IMMUNOLOGY (2006)

Article Biochemistry & Molecular Biology

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity

LY Hao et al.

Article Multidisciplinary Sciences

Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

M Armanios et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Multidisciplinary Sciences

Effects of telomerase and telomere length on epidermal stem cell behavior

I Flores et al.

SCIENCE (2005)

Review Biochemistry & Molecular Biology

The many facets of H/ACA ribonucleoproteins

UT Meier

CHROMOSOMA (2005)

Article Biochemistry & Molecular Biology

Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice

E González-Suárez et al.

ONCOGENE (2005)

Article Multidisciplinary Sciences

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

N Erdmann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Biochemistry & Molecular Biology

ATM and ataxia telangiectasia - Second in Molecular Medicine Review Series

PJ McKinnon

EMBO REPORTS (2004)

Article Multidisciplinary Sciences

Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing

Y Mochizuki et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

DNA damage checkpoint kinase Chk2 triggers replicative senescence

W Gire et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

End resection initiates genomic instability in the absence of telomerase

JA Hackett et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Multidisciplinary Sciences

A DNA damage checkpoint response in telomere-initiated senescence

FD di Fagagna et al.

NATURE (2003)

Review Hematology

The role of stem cells in aging

G Van Zant et al.

EXPERIMENTAL HEMATOLOGY (2003)

Article Biochemistry & Molecular Biology

Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells

A Satyanarayana et al.

EMBO JOURNAL (2003)

Letter Biochemistry & Molecular Biology

Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells

RC Allsopp et al.

NATURE MEDICINE (2003)

Article Multidisciplinary Sciences

Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification

D Ruggero et al.

SCIENCE (2003)

Article Hematology

Telomere maintenance in human B lymphocytes

UM Martens et al.

BRITISH JOURNAL OF HAEMATOLOGY (2002)

Article Biochemistry & Molecular Biology

Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development

E González-Suárez et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

SU Wiemann et al.

FASEB JOURNAL (2002)

Article Multidisciplinary Sciences

Constitutive telomerase expression promotes mammary carcinomas in aging mice

SE Artandi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Accelerated telomere shortening in Fanconi anemia fibroblasts - a longitudinal study

C Adelfalk et al.

FEBS LETTERS (2001)

Article Cell Biology

Telomere dysfunction triggers developmentally regulated germ cell apoptosis

MT Hemann et al.

MOLECULAR BIOLOGY OF THE CELL (2001)

Letter Genetics & Heredity

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

KL Rudolph et al.

NATURE GENETICS (2001)

Review Cell Biology

Cellular senescence as a tumor-protection mechanism: the essential role of counting

WE Wright et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2001)

Article Biochemistry & Molecular Biology

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo

Y Liu et al.

CURRENT BIOLOGY (2000)

Article Biochemistry & Molecular Biology

Wild-derived inbred mouse strains have short telomeres

MT Hemann et al.

NUCLEIC ACIDS RESEARCH (2000)

Article Genetics & Heredity

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis

E González-Suárez et al.

NATURE GENETICS (2000)

Article Multidisciplinary Sciences

Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery

KL Rudolph et al.

SCIENCE (2000)

Article Biochemistry & Molecular Biology

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast

P Dumont et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)

Article Biochemistry & Molecular Biology

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts

T Von Zglinicki et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)