Journal
INFECTION AND IMMUNITY
Volume 74, Issue 3, Pages 1958-1961Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.74.3.1958-1961.2006
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Glanders is a debilitating disease with no vaccine available. Murine monoclonal antibodies were produced against Burkholderia mallei, the etiologic agent of glanders, and were shown to be effective in passively protecting mice against a lethal aerosol challenge. The antibodies appeared to target lipopolysaccharide. Humoral antibodies may be important for immune protection against B. mallei infection.
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