Related references
Note: Only part of the references are listed.Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk
Gary R. Mirams et al.
CARDIOVASCULAR RESEARCH (2011)
Novel Approaches to Assessing Cardiac Safety – Proceedings of a Workshop
Katherine Fletcher et al.
DRUG SAFETY (2011)
High-throughput functional curation of cellular electrophysiology models
Jonathan Cooper et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2011)
An introduction to QT interval prolongation and non-clinical approaches to assessing and reducing risk
C. E. Pollard et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations
A. Corrias et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2010)
Chaste: A test-driven approach to software development for biological modelling
Joe Pitt-Francis et al.
COMPUTER PHYSICS COMMUNICATIONS (2009)
Late sodium current in the pathophysiology of cardiovascular disease: consequences of sodium-calcium overload
D Noble et al.
HEART (2006)
Non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death
SMJM Straus et al.
EUROPEAN HEART JOURNAL (2005)
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
WS Redfern et al.
CARDIOVASCULAR RESEARCH (2003)
Models of cardiac ventricular action potentials: iterative interaction between experiment and simulation
D Noble et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2001)