Journal
ANIMAL MODELS: THEIR VALUE IN PREDICTING DRUG EFFICACY AND TOXICITY
Volume 1245, Issue -, Pages 44-47Publisher
BLACKWELL SCIENCE PUBL
DOI: 10.1111/j.1749-6632.2011.06324.x
Keywords
torsade de pointes; cardiac toxicity; computer modeling; hERG
Categories
Funding
- GlaxoSmithKline Plc.
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Cardiac simulation is used to integrate information on drug action to predict side effects on the whole heart. Could simulation begin to replace animal models?
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