4.7 Article Proceedings Paper

Is it time for in silico simulation of drug cardiac side effects?

Publisher

BLACKWELL SCIENCE PUBL
DOI: 10.1111/j.1749-6632.2011.06324.x

Keywords

torsade de pointes; cardiac toxicity; computer modeling; hERG

Funding

  1. GlaxoSmithKline Plc.

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Cardiac simulation is used to integrate information on drug action to predict side effects on the whole heart. Could simulation begin to replace animal models?

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