Journal
TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY
Volume 1163, Issue -, Pages 154-168Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1749-6632.2009.04460.x
Keywords
sex steroid receptor; evolution; neurodistribution; androgen receptor
Funding
- Italian Ministero dell'Universita e della Ricerca
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This review focuses on our current understanding of vertebrate sex steroid receptors, with an emphasis on their evolutionary relationships. These relationships are discussed based on nucleotide and amino acid sequence data, which provide clues to the process by which structure-function relations have originated, evolved, and been maintained over time. The importance of the distribution of sex steroid receptors in the vertebrate brain is discussed using the example of androgen receptor sites and their relatively conserved localizations in the vertebrate brain.
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