Journal
BASIC AND CLINICAL ASPECTS OF VERTIGO AND DIZZINESS
Volume 1164, Issue -, Pages 482-485Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1749-6632.2008.03717.x
Keywords
cerebellum; rhesus; monkey; ataxia; oscillopsia
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Funding
- National Institutes of Health [ROI-EY01849]
- Arnold Chiari Foundation
- Albert Pennington Fund
- NATIONAL EYE INSTITUTE [R01EY001849] Funding Source: NIH RePORTER
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In two monkeys, we recorded spontaneous eye movements before and after ablation of the cerebellar nodulus and uvula (Nod/Uv). In both monkeys, there was an increase in upward ocular drift (downbeat nystagmus [DBN]) in darkness (M1: 1.5 degrees/s pre, 3.4 degrees/s post; M2: 1.3 degrees/s pre, 7.0 degrees/s post), but not in light. There was little effect of orbital position on drift velocity. These findings suggest that the Nod/Uv may play a role in the bias component of DBN.
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