Journal
STRESS, NEUROTRANSMITTERS, AND HORMONES: NEUROENDOCRINE AND GENETIC MECHANISMS
Volume 1148, Issue -, Pages 136-140Publisher
WILEY-BLACKWELL
DOI: 10.1196/annals.1410.083
Keywords
neuropeptide Y; animal model; anxiety; stress; Y1 receptor; alcohol
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One of the most profound properties of central neuropeptide Y (NPY) is its anxiolytic, or anti-anxiety, effect. This has been demonstrated repeatedly in a number of animal models. In addition, stressors affect NPY expression in the central nervous system, with acute and repeated (chronic) stress having differential effects. Here, a brief summary of some work performed in our laboratory is presented that supports a role for NPY in regulation of stress responses and behaviors.
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