Journal
ORGANIC LETTERS
Volume 8, Issue 6, Pages 1165-1168Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol060016f
Keywords
-
Categories
Funding
- NIGMS NIH HHS [R01 GM070483-02, R01 GM070483, GM70483] Funding Source: Medline
Ask authors/readers for more resources
Synthesis of the cyclic tetrapeptide comprising the right-hand ring of celogentin C, a potent inhibitor of tubulin polymerization, has been accomplished. A mild oxidative coupling reaction permitted construction of the indole-imidazole linkage via a convergent union of two fully functionalized dipeptides. A high-yielding macrolactamization and subsequent deprotection of the N-terminus furnished the target compound.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available