Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 71, Issue 6, Pages 2493-2498Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo052636k
Keywords
-
Categories
Funding
- NCRR NIH HHS [S10 RR016640-01] Funding Source: Medline
- NIGMS NIH HHS [R01 GM035249-18, R01 GM035249, GM35249] Funding Source: Medline
Ask authors/readers for more resources
The sequential, stereoselective disubstItUtion of 1,1-dibromoalkenes using a variety of alkenyltrifluoroborates followed by alkyltrifluoroborates in the presence of Pd(PPh3)(4) is described. This synthetic method proceeds smoothly in one Pot under mild reaction conditions to provide the corresponding trisubstituted, conjugated dienes in excellent yield. Moreover, the method is operationally very simple because the organotrifluoroborates are stable in air, and the byproducts are innocuous inorganic salts.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available