4.4 Article

Rapid and efficient synthesis of 2-imidazolines and bis-imidazolines under ultrasonic irradiation

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 13, Pages 2129-2132

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.01.127

Keywords

nitrile; imidazoline; ultrasonic irradiation; ethylenediamine

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Rapid and efficient preparation of 2-imidazolines and bis-imidazolines by reaction of ethylenediamine with nitriles in the presence of catalytic amounts of sulfur under ultrasonic irradiation is reported. The advantages of this system are short reaction times, high yields and the ability to carry out large scale reactions. (c) 2006 Elsevier Ltd. All rights reserved.

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