β-Cyclodextrin incorporated carbon nanotube-modified electrode as an electrochemical sensor for rutin

An electrochemical sensor modified with multi-walled carbon nanotubes/beta-cyclodextrin (MWNTs/beta-CD) film was fabricated for the determination of rutin. The electrochemical behavior of rutin at the chemically modified electrode was investigated by cyclic voltammetry (CV). The response mechanism of MWNTs/beta-CD film for rutin was based on the inclusion interaction of P-CD for rutin. The MWNTs/beta-CD film showed preferably analytical performance characteristics in electrocatalytic oxidation and reduction for rutin compared with the MWNTs film and bare glassy carbon electrode (GCE). A linear calibration plot was obtained covering the range from 4.0 x 10(-7) to 1.0 x 10(-3) mol L-1 with a detection limit of 2.0 x 10(-7) mol L-1. This electrochemical sensor showed excellent sensitivity, selectivity, stability and recovery for the determination of rutin in urine samples. (c) 2005 Published by Elsevier B.V.