4.7 Article

Solid-supported acids for debenzylation of aryl benzyl ethers

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 71, Issue 7, Pages 2892-2895

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo052337v

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Solid-supported acids have been investigated for aromatic debenzylation reactions. Stoichiometric amounts of solid-supported acids in refluxing toluene with or without 4 equiv of methanol effectively provided the desired aromatic debenzylation products of various systems in moderate to excellent yields (up to 98%).

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