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The immunobiology of Acanthamoeba keratitis

Journal

MICROBES AND INFECTION
Volume 8, Issue 5, Pages 1400-1405

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2005.12.009

Keywords

amoeba; keratitis; cornea; immunology

Funding

  1. NEI NIH HHS [EY09756, R24 EY016664] Funding Source: Medline

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Acanthamoeba spp. are free-living amoebae that cause Acanthamoeba keratitis, a blinding corneal infection. The innate immune apparatus is crucial for the resolution of the disease. With the exception of mucosal antibody, elements of the adaptive immune system fail to prevent infection or contribute to its resolution in experimental animals. (c) 2006 Elsevier SAS. All fights reserved.

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