Journal
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Volume 32, Issue 2, Pages 217-220Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1365-2990.2005.00692.x
Keywords
brain neoplasms; glioneuronal tumour; rosette
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We describe three unusual tumours characterized by a mixture of glial and neuronal differentiation, involvement of the posterior fossa and formation of rosettes. Mixed glial-neuronal tumours of the posterior fossa are rare and poorly described neoplasms. However, several distinctive entities have appeared in the literature over recent years under a variety of different names. Our cases demonstrate the morphological features of the 'rosette-forming glioneuronal tumour of the fourth ventricle', a recently identified tumour characterised by its unique location, neurocytic pseudo-rosette formation and the presence of a low grade astrocytoma component. The long term prognosis of these tumours remains unclear. However, the clinical data available including the cases presented here, along with the histological features, suggest that these are low grade tumours with a good prognosis after surgical resection.
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