Mononuclear copper active-oxygen complexes

There have been significant advances in the understanding of the dioxygen-activation chemistry of mononuclear copper monooxygenases such as pepticlylglycine alpha-amidating monooxygenase and dopamine beta-monooxygenase (D beta M). Recent structural and spectroscopic studies on a series of biomimetic model compounds have provided new and valuable insights into the key reactive intermediates involved in the dioxygen processing at the mononuclear copper reaction centers in biological systems.