Journal
ANNALS OF SURGERY
Volume 259, Issue 4, Pages 642-648Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/SLA.0000000000000361
Keywords
epigenetics; genetics; metabolic thrift; obesity; thrifty genotype; thrifty phenotype
Categories
Funding
- National Institutes of Health [K08DK074397, R03DK095050, R01DK097449]
Ask authors/readers for more resources
Evolution has molded metabolic thrift within humans, a genetic heritage that, when thrust into our modern obesogenic environment, creates the current obesity crisis. Modern genetic analysis has identified genetic and epigenetic contributors to obesity, an understanding of which will guide the development of environmental, pharmacologic, and genetic therapeutic interventions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available