Chemical constituents of the Vietnamese inedible mushroom Xylaria intracolorata

Investigation of the methanolic extract of Vietnamese inedible Xylariaceous mushroom Xylaria intracolorata resulted in the isolation of two new compounds named coloratin A [3,5-dimethoxy-2-(6-oxo-5-pentyl-6H-pyran-3-carbonyl)-benzoic acid] (1) and coloratin B (2-carbomethoxyl-3,5-dimethoxybenzoic acid) (2). Their structures were elucidated by 2D-NMR, MS, IR, and UV spectroscopy. Coloratin A (1) showed strong antimicrobial activity.