Journal
BIOLOGY OF THE CELL
Volume 98, Issue 4, Pages 203-214Publisher
WILEY
DOI: 10.1042/BC20050050
Keywords
adult stem cell; myoblast; satellite cell; skeletal muscle; tissue engineering
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Skeletal muscle is one of the few adult tissues that possesses the capacity for regeneration (restoration of lost functional tissue) as opposed to repair. This capacity is due to the presence of 'muscle stem cells' known as satellite cells. Detailed investigation of these cells over the past 50 years has revealed that both these and other cells within the skeletal muscle complex are capable of regenerating both muscle and other cell types as well. Here, we review this information, and suggest that skeletal muscle is an exciting reservoir of cells for regenerating skeletal muscle itself, as well as other cell types.
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