Journal
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Volume 17, Issue 2, Pages 303-313Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2006.02.002
Keywords
DiI; calcium waves; IP3 receptors; MPF; MAPK
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The endoplasmic reticulum (ER) of eggs is a major internal store of calcium ions that must be properly mobilized at fertilization for development to proceed. In most species, the ER develops distinct clusters in the cortical ooplasm as the oocyte matures into a fertilizable egg. Following fertilization, the structure of the ER rapidly reorganizes in eggs that produce a single fertilization-induced calcium wave, whereas ER clusters persist for relatively long periods in eggs that generate multiple calcium oscillations. This review considers such pre- and post-fertilization reorganizations of the ER and what effects these changes might have on calcium signaling patterns. (c) 2006 Elsevier Ltd. All rights reserved.
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