Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 7, Issue 4, Pages 265-275Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm1890
Keywords
-
Categories
Ask authors/readers for more resources
The shapes of eukaryotic cells and ultimately the organisms that they form are defined by cycles of mechanosensing, mechanotransduction and mechanoresponse. Local sensing of force or geometry is transduced into biochemical signals that result in cell responses even for complex mechanical parameters such as substrate rigidity and cell-level form. These responses regulate cell growth, differentiation, shape changes and cell death. Recent tissue scaffolds that have been engineered at the micro- and nanoscale level now enable better dissection of the mechanosensing, transduction and response mechanisms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available