Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 18, Issue 2, Pages 137-144Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2006.02.008
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The packaging of DNA into chromatin creates a number of significant barriers to the detection of DNA lesions and their timely and accurate repair. Eukaryotic cells have evolved a number of enzymes that modulate chromatin structure and facilitate DNA repair. Recent research illustrates how nucleosome remodelling enzymes cooperate with both DNA-damage-inducible and constitutive histone modifications to promote many facets of the cellular response to DNA damage.
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