Journal
IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING
Volume 3, Issue 2, Pages 159-168Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TASE.2006.871480
Keywords
contact dynamics; deoxyribonucleic-acid (DNA) chips; microarrays; microfabrication; micro/nanoscale dynamics; modeling
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Oligo deoxyribonucleic-acid (DNA) microarrays are fabricated through in-situ chemical synthesis. Contact and fluid dynamics contribute to this process. To produce high-quality oligo DNA microarrays, it is important to well understand the dynamics of the fabrication process. Much work has been done in understanding the chemistry principles. However, few studies have been conducted from the mechanics point of view. This paper proposes a contact dynamics model of inkjet technology-based oligo DNA microarray spotting process. The proposed dynamics model can reasonably well explain the dynamics of the oligo DNA microarray spotting process.
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