Journal
TETRAHEDRON
Volume 62, Issue 14, Pages 3435-3438Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.01.048
Keywords
diastereoselective synthesis; pyridine carboxaldehydes; acetylenic esters; 1-alkyl imidazoles; 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazines
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1-Alkyl imidazoles react smoothly with dialkyl acetylenedicarboxylates in the presence of pyridine carboxaldehydes to diastereoselectively produce 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazine derivatives in excellent yields. (c) 2006 Elsevier Ltd. All rights reserved.
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