Journal
LANGMUIR
Volume 22, Issue 8, Pages 3461-3463Publisher
AMER CHEMICAL SOC
DOI: 10.1021/la0534468
Keywords
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Funding
- NHLBI NIH HHS [R01 HL062244-05A1, R01 HL062244, R01 HL062244-06] Funding Source: Medline
- NIGMS NIH HHS [R01 GM038060, R01 GM038060-18, R01 GM038060-17] Funding Source: Medline
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Although nanotechnology has provided a rich variety of nanomaterials (1 - 100 nm) for in vivo medical applications, the blood compatibility of all these nanobiomaterials is still largely unexamined. Here, we report the preparation of blood-compatible carbon nanotubes (CNTs) that potentially represent the building blocks for nanodevices having in vivo applications. Activated partial thromboplastin time (APTT) and thromboelastography (TEG) studies prove that heparinization can significantly enhance the blood compatibility of nanomaterials.
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