4.6 Article

Fiber-optic scanning two-photon fluorescence endoscope

Journal

OPTICS LETTERS
Volume 31, Issue 8, Pages 1076-1078

Publisher

OPTICAL SOC AMER
DOI: 10.1364/OL.31.001076

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Funding

  1. Directorate For Engineering
  2. Div Of Chem, Bioeng, Env, & Transp Sys [0940321] Funding Source: National Science Foundation

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We report on the development of a miniature, flexible, fiber-optic scanning endoscope for two-photon fluorescence imaging. The endoscope uses a tubular piezoelectric actuator for achieving two-dimensional beam scanning and a double-clad fiber for delivery of the excitation light and collection of two-photon fluorescence. Real-time imaging of fluorescent beads and cancer cells has been performed. (c) 2006 Optical Society of America.

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