Journal
BRAIN RESEARCH
Volume 1085, Issue -, Pages 132-137Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.brainres.2006.02.087
Keywords
transient receptor potential (TRP); channel; TRPC; rat; hippocampus; immunohistochemistry
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In the present study, we performed immunohistochemistry using antibodies directed against TRPCs to study the localizations of these channels in rat hippocampus. The pyramidal cell bodies of CA1-3 areas and the granule cell bodies of the dentate gyrus were immunoreactive for TRPC1, TRPC3, TRPC4 and TRPC5. On the other hand, TRPC6 exhibited the cloud-like neuropil staining only in the molecular layer of the dentate gyrus. As a whole, the present study has clearly shown the localization of TRPCs in rat hippocampus and may provide useful data for the future investigations on the structural and functional properties of TRPCs. (c) 2006 Elsevier B.V. All rights reserved.
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