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Potent antibody therapeutics by design

Journal

NATURE REVIEWS IMMUNOLOGY
Volume 6, Issue 5, Pages 343-357

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NATURE PUBLISHING GROUP
DOI: 10.1038/nri1837

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Antibodies constitute the most rapidly growing class of human therapeutics and the second largest class of drugs after vaccines. The generation of potent antibody therapeutics, which I review here, is an iterative design process that involves the generation and optimization of antibodies to improve their clinical potential.

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