Journal
INFECTION AND IMMUNITY
Volume 74, Issue 5, Pages 3002-3005Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.74.5.3002-3005.2006
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Funding
- NIDCR NIH HHS [R01 DE011111, DE12505, R37 DE011111, R01 DE012505, DE11111] Funding Source: Medline
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The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InIJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InIJ in regulating biofilm accumulations of P. gingivalis.
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