Journal
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
Volume 20, Issue 12, Pages 1998-2002Publisher
WILEY
DOI: 10.1111/1756-185X.12613
Keywords
arterial hypertension; arterial stiffness; atherosclerosis; carotid intima-media thickness; rheumatoid arthritis
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Funding
- Ministry of Science, Education and Sport, the Republic of Croatia [198-1081874-0183]
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AimRheumatoid arthritis is associated with accelerated atherosclerosis. However, little is known about preclinical atherosclerosis in hypertensive rheumatoid arthritis patients. In this cross-sectional study we assessed the expression of preclinical atherosclerosis in hypertensive rheumatoid arthritis patients in comparison with matched hypertensive non-rheumatoid arthritis patients. MethodsThe study included 52 hypertensive rheumatoid arthritis patients and 42 hypertensive non-rheumatoid arthritis patients. The patients were extensively examined clinically and laboratory tested. The expression of preclinical atherosclerosis was estimated by assessing ambulatory arterial stiffness index and common carotid intima-media thickness. ResultsArterial stiffness index and common carotid intima-media thickness were higher in hypertensive rheumatoid arthritis patients than in hypertensive non-rheumatoid arthritis patients. There was no correlation between arterial stiffness index and common carotid intima-media thickness with markers of inflammation and disease activity in hypertensive rheumatoid arthritis patients. ConclusionThe expression of subclinical atherosclerosis is more pronounced in hypertensive rheumatoid arthritis than in hypertensive non- rheumatoid arthritis patients.
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