Journal
BRITISH JOURNAL OF HAEMATOLOGY
Volume 133, Issue 4, Pages 364-374Publisher
WILEY
DOI: 10.1111/j.1365-2141.2006.06024.x
Keywords
thrombocytopaenia; immune thrombocytopaenic purpura; pathology; T cells; cytokines
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Immune thrombocytopaenic purpura (ITP) is an autoimmune bleeding disease that is rarely fatal. However, in many adults treatment is unsatisfactory, with as much morbidity from the immunosuppressive effects of treatment as from bleeding. Identifying the underlying disease process should help us to identify more targeted therapies and improve not only the treatment but also the quality of life of patients with this disorder.
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