Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 54, Issue 5, Pages S255-S261Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2005.12.042
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This article focuses on developments in pigmentary disorders that extend dermatologists' Understanding of the field. Areas that are reviewed include the basic biochemistry, pharmacology, and physiology of the melanocortin system; melanosome development; genetic diseases associated with pigmentary disorders; pigmentary disorders secondary to systemic disease; drug-induced hyperpigmentation; environmental exposure to chemicals; and primary disorders of hyperpigmentation such as melasma and lentigines. Basic, clinical, and epidemiological research, along with a number of clinical case reports, were included in the review. This article also reports on the new health-related quality-of-life instrument (MELASQOOL) that has been developed for women with melasma.
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