Journal
JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B
Volume 15, Issue 3, Pages 220-221Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.bpb.0000194439.75378.ac
Keywords
bone morphogenetic protein-7; congenital pseudarthrosis of tibia; osteogenic protein-1
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Congenital pseudarthrosis of the tibia remains one of the most difficult orthopaedic problems to treat. Before the use of a recombinant bone morphogenetic protein (bone morphogenetic protein-7; osteogenic protein-1) the patient with congenital pseudarthrosis of the tibia in this report had had 12 unsuccessful surgeries. Five months after radical resection of sclerotic tibial segments, llizarov fixation and administration of osteogenic protein-1 osteogenic device, the congenital pseudarthrosis of the tibia healed; at 45 months the tibia increased in size and the patient was fully weight bearing.
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