Role of mitochondria in multiple sclerosis

This review presents inherited and acquired forms of mitochondrial dysfunction associated with oligodendrocytopathy and neurodegeneration in order to better understand the degenerative features of inflammatory demyelination. The recogniton that various mitochondrial mechanisms. the recogniton that various mitochondrial mechanisms are involved in the pathogenesis of multiple sclerosis leads to therapeutic considerations, re-emphasizing the importance of early neuroprotection in combination with the approved means of immune modulation.