Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 26, Issue 2, Pages 283-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2006.02.009
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Allergen-specific immunotherapy is currently the only curative treatment for allergy Subcutaneous immunotherapy (SCIT) has been successfully used to treat patients who are allergic to insect venom, house dust mites, or tree or grass pollens. In the context of potentially severe, albeit infrequent, side effects associated with SCIT, mucosal routes of administration are being investigated to conduct allergenic desensitization. This article reviews recent developments in the field of nasal, oral, and sublingual immunotherapy as they relate to safety, clinical efficacy, and immune mechanisms of action.
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