Journal
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Volume 17, Issue 5, Pages 1224-1234Publisher
AMER SOC NEPHROLOGY
DOI: 10.1681/ASN.2005080882
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Wegener's granulomatosis, microscopic polyangiitis, and renal limited vasculitis are associated with circulating anti-neutrophil cytoplasm antibodies and are an important cause of rapidly progressive glomerulortephritis. This review gives an account of recent advances in the understanding of the pathogenesis underlying these conditions and how these may lead to future treatments. Consideration is given to recent clinical trials in the management of anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitides.
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