4.7 Article

Curcumin-artemisinin combination therapy for malaria

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 50, Issue 5, Pages 1859-1860

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.50.5.1859-1860.2006

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Artemisinin and curcumin show an additive interaction in killing Plasmodiunt falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of alpha,beta-arteether to Plasmodium bergitei-infected mice are able to prevent recrudescence due to alpha,beta-arteether monotherapy and ensure almost 100% survival of the animals.

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