Stoller afferent nerve stimulation in woman with therapy resistant over active bladder; a 1-year follow up

Aim: In this prospective observational study, we investigated the efficacy of Stoller afferent nerve stimulation (SANS) in subjects with overactive bladder who failed anticholinergic treatment. Methods: Thirty-five subjects with overactive bladder who failed therapy with oxybutynin participated in this study. Treatment (n=35) was given once a week for 30 minutes for overall 10 weeks. In treatment, SANS device (Urosurge(R)) was used. Subjects were assessed with 3-day voiding diary, SEAPI quality of life questionnaires and cystometry before therapy after completion of therapy and at one-year follow-up. Results: In 54% (n=19) of subjects complete recovery was obtained after treatment. Urgency and SEAPI were reduced significantly whereas urine volume increased significantly (p < 0.01). Complete recovery was maintained in eight of the 19 subjects at one year. Conclusions: SANS treatment has a short-term positive effect in patients with resistant overactive bladder. However, it was also established that efficacy was maintained at 1 year in only 23% of subjects.