Journal
OCCUPATIONAL MEDICINE-OXFORD
Volume 56, Issue 3, Pages 162-172Publisher
OXFORD UNIV PRESS
DOI: 10.1093/occmed/kql011
Keywords
combined injury; gastrointestinal syndrome; haematopoietic syndrome; internal contamination; local radiation injury; radiation injury; radiation medicine
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The current approach to medical management of irradiated patients begins with early diagnosis of radiation injury. Medical assessment of radiation dose is based on event history, symptomatology and laboratory results, with emphasis on time to emesis and lymphocyte depletion kinetics. Dose assessment provides a basis for early use of haematopoietic growth factors that can shorten the period of neutropaenia for patients with acute radiation syndrome. Assessments of haematopoietic, gastrointestinal and cutaneous syndromes have improved in recent years, but treatment options remain limited. Selected examples of current developments are presented.
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