Journal
TETRAHEDRON
Volume 62, Issue 18, Pages 4342-4348Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.02.072
Keywords
isatin; spirocyclopropane; sodium borohydride; 2-indalones; Baylis-Hillman adduct
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A facile, high yield stereoselective synthesis of functionalized diastereomeric 3 -spirocyclopropane-2-indolones (10-17a,b) from the isomerised bromo derivatives of Baylis-Hillman adducts of isatin(2-9a,b) by reductive cyclization with sodium borohydride is reported. (c) 2006 Elsevier Ltd. All rights reserved.
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