4.1 Review

COPI-mediated transport

Journal

JOURNAL OF MEMBRANE BIOLOGY
Volume 211, Issue 2, Pages 65-79

Publisher

SPRINGER
DOI: 10.1007/s00232-006-0859-7

Keywords

membrane transport; membrane transport mechanisms; SNARE biochemistry

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COPI-coated vesicles are protein and liquid carriers that mediate transport within the early secretory pathway. In this Topical Review, we present their main protein components and discuss current models for cargo sorting. Finally, we describe the striking similarities that exist between the COPI system and the two other characterized types of vesicular carriers: COPII- and clathrin-coated vesicles.

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