Journal
ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE
Volume 160, Issue 5, Pages 502-507Publisher
AMER MEDICAL ASSOC
DOI: 10.1001/archpedi.160.5.502
Keywords
-
Categories
Ask authors/readers for more resources
Objective: To assess the evidence that early solid feeding ( before age 4 months) increases the risk of allergic disease. Data Sources: MEDLINE, the Cochrane Library, and the Drugs and Pharmacology section of EMBASE with key words infant, food, and allergy. Study Selection: We found 2719 article citations and reviewed references of relevant articles. We critically evaluated the methods and results of articles that met inclusion criteria. We identified 13 studies that met inclusion criteria. There was only 1 controlled trial. Data Extraction: Allergic disease. Data Synthesis: Five studies found a positive association between early solid feeding and eczema, with a persistence of the association for 10 years in 1 study. Four studies found no association. One study found an association between early solid feeding and pollen allergy. We found no strong evidence to support the association between early solid feeding and the development of persistent asthma, persistent food allergy, allergic rhinitis, or animal dander allergy. Conclusions: Systematic review of available evidence suggests that early solid feeding may increase the risk of eczema. However, there are little data supporting an association between early solid feeding and other allergic conditions. Since many studies had problematic methods, additional controlled trials are needed to help guide physicians as they advise parents about the allergic risks of early introduction of solids.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available