Journal
JOURNAL OF PROTEOME RESEARCH
Volume 5, Issue 5, Pages 1276-1278Publisher
AMER CHEMICAL SOC
DOI: 10.1021/pr050450w
Keywords
nanobacteria; arthritis; synovial fluid; rheumatoid arthritis; osteoarthritis; microorganisms
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We investigated the existence of nanosize particles in synovial fluids of rheumatoid arthritis and osteoarthritis patients. These specimens were cultured under mammalian cell culture conditions (37 degrees C; 5% CO2/95% air) for a long period. After about 2 months, many nanoparticles appeared and they gradually increased in number and in size. The nanobacteria-like particles exist in synovial fluids of arthritis patients. The possibility of their existence and pathogenesis in various diseases should be verified cautiously.
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