Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 25, Issue 5, Pages 490-500Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2005.11.013
Keywords
bioimaging; DNA hybridization; immunoassay; lanthanide; luminescence probe
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Time-resolved luminescence bioassays based on lanthanide-luminescence probes have become common, useful tools in clinical diagnostics and bioanalytical chemistry. The unique spectral and temporal properties of lanthanide-luminescence probes, such as very long luminescence lifetime, large Stokes Shift and sharp emission profile, make them an ideal choice for use in time-resolved luminescence bioassays to discriminate background noises effectively. This review gives an overview of recent developments in lanthanide-luminescence probes and their applications in time-resolved luminescence bioassays. (c) 2005 Elsevier Ltd. All rights reserved.
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