Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 103, Issue 18, Pages 6790-6792Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.0601743103
Keywords
magnetic resonance imaging; radiation-free imaging; sensitivity
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Funding
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [0815865] Funding Source: National Science Foundation
- NIGMS NIH HHS [P41 GM066354] Funding Source: Medline
- PHS HHS [P41 FM66354] Funding Source: Medline
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NMR images were obtained from the proton spin noise signals of a water-containing phantom, which was placed in the highly tuned, low-noise resonant circuit of a cryogenically cooled NMR probe in the presence of systematically varied magnetic field gradients. The spatially resolved proton spin density was obtained from the raw signal by a modified projection-reconstruction protocol. Although spin noise imaging is inherently less sensitive than conventional magnetic resonance imaging, it affords an entirely noninvasive visualization of the interior of opaque objects or subjects. Thus, tomography becomes possible even when neither x-ray nor radio frequency radiation can be applied for technical or safety reasons.
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