Journal
SYNLETT
Volume -, Issue 7, Pages 1063-1066Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-939705
Keywords
catalysis; substituent effects; regioselectivity; Friedel-Crafts reaction; acylations
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A correlation was found between electronic properties and regioselectivity in the Friedel-Crafts reaction of substituted phenylacetic and benzoic acids with anisole, utilising substoichio-metric (down to 1 mol%) amounts of catalyst. Relative reactivities of selected catalysts for this reaction were also studied.
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