4.4 Article

An efficient chemoenzymatic route to dihydroxy acetone phosphate from glycidol for the in situ aldolase-mediated synthesis of monosaccharides

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 19, Pages 3261-3263

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.03.036

Keywords

DHAP; multienzymatic synthesis; aldolase; C-C bond formation

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We report a new two-step procedure that uses inexpensive rac-glycidol to obtain valuable dihydroxyacetone phosphate (DHAP), a building block for the synthesis of monosaccharide analogues. (c) 2006 Elsevier Ltd. All rights reserved.

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